Marihuana inhibits dihydrotestosterone binding to the androgen receptor
V Purohit, BS Ahluwahlia and RA Vigersky
Marihuana and its constitutents delta 9-tetrahydrocannabinol (delta 9- THC) and cannabinol (CBN) were tested for their ability to interact with the androgen receptor in rat prostate cytosol. Smoked marihuana condensate, delta 9-THC, and CBN inhibit specific binding of dihydrotestosterone (DHT) to the androgen receptor with a dissociatin constant of the inhibitors (Li) of 2.1-5.8 X 10(-7)M. in addition, other metabolites of delta 9-THC were also androgen antagonists. This data suggests that the anti-androgenic effects associated with marihuana use results, at least in part, from inhibition of androgen action at the receptor level.
klingt fast so gut wie fluta, aber keiner spricht darüber
und ja ich weiß dass es schonmal threads darüber gab
[Aktualisiert am: Sa., 19 April 2008 18:57]
anagain, minox
"Wenn Sperma in der Lage ist neues Leben zu zeugen (Kinder), warum dann nicht auch neue Follikel?" (Ab-2008-Norwood-Null)