Akne und 17-OHP [Beitrag #13587] :: Sa., 04 März 2006 17:30 
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tristan
Beiträge: 709 Registriert: November 2005
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Der Zusammenhang ist mir mittlerweile eh klar, aber schön dass es auch mal aus Dermatologie-bereichen kommt...
Journal of the American Academy of Dermatology
Volume 53, Issue 6 , December 2005, Pages 955-958
doi:10.1016/j.jaad.2005.07.014
2005 American Academy of Dermatology, Inc.
Published by Mosby, Inc.
Report
Elevated 17-hydroxyprogesterone serum values in male patients with acne
Marianne Placzek MDa, Barbara Arnold MDa, Heinrich Schmidt MDb, Sabine Gaube MDa, Elisabeth Keller PhDb, Gerd Plewig MDa and Klaus Degitz MDa, Corresponding Author Contact Information, E-mail The Corresponding Author
aFrom the Departments of Dermatology
bPediatrics, Ludwig-Maximilian-University
Accepted 5 July 2005. Munich, Germany.
Available online 5 October 2005.
Background
Androgen excess may provoke or aggravate acne by inducing seborrhea. In women,next term androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.
Objective
Our aim was to investigate whether male patients with acne display pathologic androgen blood values.
Methods
This case-control study at a university dermatology department with referred and unreferred patients investigated male acne patients (n = 82, consecutive sample) in whom the diagnosis of mild to severe acne was made, as well as a control group of men without acne (n = 38). The main outcome measures were androgen parameters including morning values of testosterone, luteinizing hormone, follicle-stimulating hormone, dehydroepiandrosterone sulfate, androstenedione, and 17-hydroxyprogesterone; as well as a corticotropin stimulation test.
Results
17-Hydroxyprogesterone levels were significantly higher (P = .01) in acne patients than in the control group, whereas the other parameters did not differ significantly. In addition, the corticotropin stimulation test revealed abnormal 17-hydroxyprogesterone induction values in 10 of 82 patients.
Limitations
The analysis is limited to a selection of androgen parameters.
Conclusion
The results suggest that in men irregularities of adrenal steroid metabolism may be a factor contributing to acne.
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Re: Akne und 17-OHP [Beitrag #13804 ist eine Antwort auf Beitrag #13798] :: Mo., 06 März 2006 17:57 
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pilos
Beiträge: 27294 Registriert: November 2005 Ort: Ausland
Power Member *****
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| asdfasdf schrieb am Mon, 06 März 2006 17:41 |
ja aber angenommen ich find raus dass ich erhöhte werte habe, dann wird des doch wenn nur sehr sehr schwierig sein diese werte zu korrigieren, oder? gibts da überhaupt medikamente dafür?
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angenommen...heist .........etwa wie glauben...und glauben heist nicht wisssen...also wenn du diese werte nicht kennst, dann versuche sie zu bekommen...spekulieren bringt nämlich wenig...
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