Studie: Finasteride 5 mg and Sexual Side Effects [Beitrag #99697] :: Di., 27 November 2007 14:11
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Figaro03
Beiträge: 1244 Registriert: Dezember 2005
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it aus der Liste, die tristan gepostet hat.
ist ja mal ultrakrass, was ein einzelner Satz macht...
Zitat: |
Methods. One hundred twenty patients with a clinical diagnosis of benign prostatic hyperplasia (BPH), sexually active and with an International Index of Erectile Function-erectile function (IIEF-EF) domain ≥25 were randomized to receive finasteride 5 mg concealed as an "X compound of proven efficacy for the treatment of BPH" for 1 year with (group 2) or without (group 1) counseling on the drug sexual side effect. The phrase used to inform group 2 patients was ". . . it may cause erectile dysfunction, decreased libido, problems of ejaculation but these are uncommon".
Main Outcome Measures. The estimation of side effect was conducted at 6 and 12 months using the male sexual function-4 (MSF-4 item) questionnaire and a self-administered questionnaire.
Results. One hundred seven patients completed the study. Group 2 patients (N = 55) reported a significant higher proportion of one or more sexual side effects as compared to group 1 (N = 52) (43.6% vs. 15.3%) (P = 0.03). The incidence of ED, decreased libido, and ejaculation disorders were 9.6, 7.7, and 5.7% for group 1, and 30.9, 23.6, and 16.3% for group 2, respectively (P = 0.02, P = 0.04, and P = 0.06).
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http://www.blackwell-synergy.com/doi/abs/10.1111/j.1743-6109 .2007.00563.x?cookieSet=1&journalCode=jsm
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